Reaction Rate Math: Difference between revisions
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The rate at which molecules interact to form a bound complex is called the ''association rate''; conversely the rate at which a bound complex breaks down into constituent parts is called the ''dissociation rate''. | The rate at which molecules interact to form a bound complex is called the ''association rate''; conversely the rate at which a bound complex breaks down into constituent parts is called the ''dissociation rate''. | ||
association rate: <code> k<sub>on</sub> </code> or <code> k<sup>+</sup> </code> µM<sup>-1</sup>s<sup>-1</sup> | |||
dissociation rate: <code> k<sub>off</sub> </code> or <code> k<sup>-</sup> </code> s<sup>-1</sup> | |||
The affinity of this binding is: | |||
affinity constant: K<sub>A</sub> = 1 / K<sub>D</sub> = k<sub>on</sub> / k<sub>off</sub> | |||
Binding is reversible, with a dissociation constant of: | |||
dissociation constant: K<sub>D</sub> = 1 / K<sub>A</sub> = k<sub>off</sub> / k<sub>on</sub> | |||
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[[Category:Math]][[Category:Neurobiology]][[Computational Neuroscience]] | |||
[[Category:Math]][[Category:Neurobiology]][[Category:Computational Neuroscience]] | |||
Latest revision as of 05:51, 7 October 2016
The rate at which molecules interact to form a bound complex is called the association rate; conversely the rate at which a bound complex breaks down into constituent parts is called the dissociation rate.
association rate:konork+µM-1s-1
dissociation rate:koffork-s-1
The affinity of this binding is:
affinity constant: KA = 1 / KD = kon / koff
Binding is reversible, with a dissociation constant of:
dissociation constant: KD = 1 / KA = koff / kon