Molecular Memory: Difference between revisions

From bradwiki
Jump to navigation Jump to search
(Adding image note: cAMP works by activating protein kinase A (PKA, cAMP-dependent protein kinase). PKA is normally inactive as a tetrameric holoenzyme, cons)
(Adding image note: 1. concentration of cAMP rises (e.g., activation of adenylate cyclase via GPCR-Gs) 2. cAMP molecules bind and release each PKA regulator)
Line 138: Line 138:
There are some minor PKA-independent functions of cAMP, e.g., activation of calcium channels, providing a minor pathway by which growth hormone-releasing hormone causes a release of growth hormone.
There are some minor PKA-independent functions of cAMP, e.g., activation of calcium channels, providing a minor pathway by which growth hormone-releasing hormone causes a release of growth hormone.
{{ImageNoteEnd|id=2}}
{{ImageNoteEnd|id=2}}
{{ImageNote|id=3|x=642|y=404|w=57|h=42|dimx=1584|dimy=1584|style=2}}
1. concentration of cAMP rises (e.g., activation of adenylate cyclase via GPCR-Gs)
2. cAMP molecules bind and release each PKA regulatory subunit.
3. catalytic subunits phosphorylate Ser and Thr residues
4. PKA can directly activate CREB, which binds CRE, altering the transcription
{{ImageNoteEnd|id=3}}
</div>
</div>
</div>
</div>

Revision as of 23:24, 14 April 2013

{{#tree:id=ConnectomeTree|openlevels=2|root=ConnectomeTree|

}}

Error creating thumbnail: File missing
Error creating thumbnail: File missing
Error creating thumbnail: File missing
Error creating thumbnail: File missing
Error creating thumbnail: File missing
Error creating thumbnail: File missing
Error creating thumbnail: File missing
Error creating thumbnail: File missing
Error creating thumbnail: File missing
Error creating thumbnail: File missing
Connectome1
Connectome2
Connectome3
Connectome4
Connectome6
Connectome8
Connectome9
Connectome10
Connectome12
Connectome15