ReDiClus: Difference between revisions
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{{Box|font=120%|width=95%|float=left|text=12px|Visual Representations| | {{Box|font=120%|width=95%|float=left|text=12px|Visual Representations|[[File:ScaleModel.png|950px]]}} | ||
[[File:ScaleModel.png|950px]] | |||
{{Box|font=120%|width=95%|float=left|text=12px|Particle Diffusion| | |||
{{Box|font=120%|width=60%|float=right|text=12px|border=dashed #FF0000 1px|Particle Diffusion| | |||
Particle diffusion is generated from Einstein's equations on Brownian motion. This allows the model to generate real-world diffusion at rates that are empirically relevant. There are currently 5 different regions in the model that can each independently scale the diffusion rate: the extrasynaptic space (ES), post-synaptic density 1 (PSD-1), post-synaptic density 2 (PSD-2) and the perisynaptic PSD-1 region (pPSD-1) and PSD-2 region (pPSD-2). The PSD and pPSD diffusion rates (D<sub>psd</sub>) can be automatically scaled in real-time by the number of PSD-95 SAP molecules currently expressed in a PSD-cluster region. For most simulations the starting SAP cluster size is 7x7 yielding 49 total SAP molecules. The amount of SAP dynamically fluctuates. It can hold a fairly steady number of about 50 SAPs, but it can also be made to grow and shrink to values ranging from 10 to 100 SAPs. The PSD diffusion rate can be scaled from these SAP values. The function for this scalar can be seen to the left. Given a range of 10 to 100 SAPs, the PSD diffusion rate values will range from 0.03 um²/s - 0.003 um²/s. | |||
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;: Base ExtraSynaptic Diffusion rate '''''D''''' (D<sub>es</sub>) | |||
* D<sub>es</sub> ≃ 0.3 um²/s | |||
* Base PSD Diffusion rates (D<sub>psd</sub>) | |||
* D<sub>psd</sub> ≃ 0.03 um²/s | |||
:: {{Up}} to {{Dn}} | |||
* D<sub>psd</sub> ≃ 0.003 um²/s | |||
<br> | |||
;: D<sub>psd</sub> SAP scalar function | |||
*D<sub>psd</sub> ≃ D<sub>es</sub>/SAP | |||
* D<sub>psd</sub> ≃ 0.3/10 ≃ 0.03 um²/s | |||
:: {{Up}} to {{Dn}} | |||
* D<sub>psd</sub> ≃ 0.3/100 ≃ 0.003 um²/s | |||
}} | }} | ||
{{Clear}} | {{Clear}} |
Revision as of 21:12, 3 September 2013
ReDiClus - Receptor Diffusion & Cluster Model
Simulation Space
ReDiClus Model Space
Particle Types
Visual Representations
Particle Diffusion
Physical Properties
ReDiClus Physics
two independent processes
MEAN SQUARED DISPLACEMENT
Data Generation
ReDiClus MODEL DATA RESULTS
Neural Anatomy
Quantitative Physiology of the Dendrite
Quantitative Review
The Size of Dendrites
Particle Counts
Diffusion Rates
Images
Choquet 2007 Real Time Receptor Diffusion
Choquet 2007 Real Time Receptor Diffusion Analysis
Receptor Diffusion Rate Best Estimates
Brain Data: Facts and Figures
Estimated Number of Neurons in the Brain of Humans & Other Animals
Brain vs Computer
Facts and Figures
Processor | Transistor count | Date of introduction | Manufacturer | Semiconductor device fabrication|Process | Area |
---|---|---|---|---|---|
Core 2 Duo Wolfdale3M | 230,000,000 | 2008 | Intel | 45 nm | 83 mm² |
Core i7 (Quad) | 731,000,000 (7e8) | 2008 | Intel | 45 nm | 263 mm² |
POWER6 | 789,000,000 | 2007 | IBM | 65 nm | 341 mm² |
WDC 65C02 | 785,000,000 | 2009 | western design center | 0.22 µm | 14 mm² |
Six-Core Opteron 2400 | 904,000,000 | 2009 | AMD | 45 nm | 346 mm² |
16-Core SPARC T3 | 1,000,000,000 (1e9) | 2010 | Sun Oracle Corporation|Oracle | 40 nm | 377 mm² |
Quad-Core plus GPU Sandy Bridge Core i7 | 1,160,000,000 | 2011 | Intel | 32 nm | 216 mm² |
Core i7 (Gulftown) | 1,170,000,000 | 2010 | Intel | 32 nm | 240 mm² |
8-core POWER7 32M L3 | 1,200,000,000 | 2010 | IBM | 45 nm | 567 mm² |
8-Core AMD Bulldozer | 1,200,000,000 | 2012 | AMD | 32nm | 315 mm² |
Quad-Core + GPU AMD Trinity | 1,303,000,000 | 2012 | AMD | 32 nm | 246 mm² |
z196 | 1,400,000,000 | 2010 | IBM | 45 nm | 512 mm² |
Core i7 | 1,400,000,000 | 2012 | Intel | 22 nm | 160 mm² |
Dual-Core Itanium 2 | 1,700,000,000 | 2006 | Intel | 90 nm | 596 mm² |
Six-Core Xeon 7400 | 1,900,000,000 | 2008 | Intel | 45 nm | 503 mm² |
Tukwila | 2,000,000,000 (2e9) | 2010 | Intel | 65 nm | 699 mm² |
8-core POWER7 80M L3 | 2,100,000,000 | 2012 | IBM | 32 nm | 567 mm² |
Six-Core Core i7 and 8-Core Xeon E5 | 2,270,000,000 | 2011 | Intel | 32 nm | 434 mm² |
Nehalem-EX | 2,300,000,000 | 2010 | Intel | 45 nm | 684 mm² |
10-Core Xeon Westmere-EX | 2,600,000,000 | 2011 | Intel | 32 nm | 512 mm² |
zEC12 | 2,750,000,000 | 2012 | IBM | 32 nm | 597 mm² |
Poulson | 3,100,000,000 (3e9) | 2012 | Intel | 32 nm | 544 mm² |
15-Core Xeon Ivy Bridge-EX | 4,310,000,000 (4e9) | 2014 | Intel | 22 nm | |
62-Core Xeon Phi | 5,000,000,000 | 2012 | Intel | 22 nm | |
Xbox One Main SoC | 5,000,000,000 (5e9) | 2013 | Microsoft/AMD | 28 nm | 363 mm² |
STARShiP | Molecular Methods | Quantum Dots | AMPAR | Brownian Motion |
Malinow | Molecular Methods | Quantum Dots | Choquet | AMPAR |