Molecular Memory: Difference between revisions
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(Adding image note: cAMP works by activating protein kinase A (PKA, cAMP-dependent protein kinase). PKA is normally inactive as a tetrameric holoenzyme, cons) |
(Adding image note: 1. concentration of cAMP rises (e.g., activation of adenylate cyclase via GPCR-Gs) 2. cAMP molecules bind and release each PKA regulator) |
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There are some minor PKA-independent functions of cAMP, e.g., activation of calcium channels, providing a minor pathway by which growth hormone-releasing hormone causes a release of growth hormone. | There are some minor PKA-independent functions of cAMP, e.g., activation of calcium channels, providing a minor pathway by which growth hormone-releasing hormone causes a release of growth hormone. | ||
{{ImageNoteEnd|id=2}} | {{ImageNoteEnd|id=2}} | ||
{{ImageNote|id=3|x=642|y=404|w=57|h=42|dimx=1584|dimy=1584|style=2}} | |||
1. concentration of cAMP rises (e.g., activation of adenylate cyclase via GPCR-Gs) | |||
2. cAMP molecules bind and release each PKA regulatory subunit. | |||
3. catalytic subunits phosphorylate Ser and Thr residues | |||
4. PKA can directly activate CREB, which binds CRE, altering the transcription | |||
{{ImageNoteEnd|id=3}} | |||
</div> | </div> | ||
</div> | </div> | ||
Revision as of 22:24, 14 April 2013
{{#tree:id=ConnectomeTree|openlevels=2|root=ConnectomeTree|
- Ligand-gated ion channels
- Voltage-gated ion channels
- Nucleosides
- Synaptic Kinases
- Transcription Factors
- Promoter Genes
- Immediate Early Genes
- G protein-coupled receptors
- 5-Hydroxytryptamine receptors
- Acetylcholine receptors (muscarinic)
- Adenosine receptors
- Adrenoceptors
- Angiotensin receptors
- Apelin receptor
- Bile acid receptor
- Bombesin receptors
- Bradykinin receptors
- Calcitonin receptors
- Calcium-sensing receptors
- Cannabinoid receptors
- Chemerin receptor
- Chemokine receptors
- Cholecystokinin receptors
- Complement peptide receptors
- Corticotropin-releasing factor receptors
- Dopamine receptors
- Endothelin receptors
- Estrogen (G protein-coupled) receptor
- Formylpeptide receptors
- Free fatty acid receptors
- Frizzleds
- GABAB receptors
- Galanin receptors
- Ghrelin receptor
- Glucagon receptor family
- Glycoprotein hormone receptors
- Gonadotrophin-releasing hormone receptors
- Histamine receptors
- Hydroxycarboxylic acid receptors
- Kisspeptin receptor
- Leukotriene receptors
- Lysophospholipid (LPA) receptors
- Lysophospholipid (S1P) receptors
- Melanin-concentrating hormone receptors
- Melanocortin receptors
- Melatonin receptors
- Metabotropic glutamate receptors
- Motilin receptor
- Neuromedin U receptors
- Neuropeptide FF/neuropeptide AF receptors
- Neuropeptide S receptor
- Neuropeptide W/neuropeptide B receptors
- Neuropeptide Y receptors
- Neurotensin receptors
- Opioid receptors
- Orexin receptors
- Oxoglutarate receptor
- P2Y receptors
- Parathyroid hormone receptors
- Peptide P518 receptor
- Platelet-activating factor receptor
- Prokineticin receptors
- Prolactin-releasing peptide receptor
- Prostanoid receptors
- Protease-activated receptors
- Relaxin family peptide receptors
- Somatostatin receptors
- Succinate receptor
- Tachykinin receptors
- Thyrotropin-releasing hormone receptors
- Trace amine receptor
- Urotensin receptor
- Vasopressin and oxytocin receptors
- VIP and PACAP receptors
- Taste 1 receptors
- Nuclear Hormone Receptors
- 1A. Thyroid Hormone receptors
- 1B. Retinoic acid receptors
- 1C. Peroxisome proliferator-activated receptors
- 1D. Rev-Erb receptors
- 1F. RAR-related orphan receptors
- 1H. Liver X receptor-like receptors]]
- 1I. Vitamin D receptor-like receptors]]
- 2A. Hepatocyte nuclear factor-4 receptors
- 2B. Retinoid X receptors
- 2C. Testicular receptors
- 2E. Tailless-like receptors
- 2F. COUP-TF-like receptors
- 3A. Estrogen receptors
- 3B. Estrogen-related receptors
- 3C. 3-Ketosteroid receptors
- 4A. Nerve growth factor IB-like receptors
- 5A. Fushi tarazu F1-like receptors
- 6A. Germ cell nuclear factor receptors
- 0B. DAX-like receptors
- Receptor Kinases
}}
