Molecular Memory: Difference between revisions

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(Adding image note: 1. concentration of cAMP rises (e.g., activation of adenylate cyclase via GPCR-Gs) 2. cAMP molecules bind and release each PKA regulator)
(Changing image note: 1. concentration of cAMP rises (e.g., activation of adenylate cyclase via GPCR-Gs) 2. cAMP molecules bind and release each PKA regula)
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{{ImageNote|id=3|x=642|y=404|w=57|h=42|dimx=1584|dimy=1584|style=2}}
{{ImageNote|id=3|x=642|y=404|w=57|h=42|dimx=1584|dimy=1584|style=2}}
1. concentration of cAMP rises (e.g., activation of adenylate cyclase via GPCR-Gs)  
1. concentration of cAMP rises (e.g., activation of adenylate cyclase via GPCR-Gs)  
2. cAMP molecules bind and release each PKA regulatory subunit.  
2. cAMP molecules bind and release each PKA regulatory subunit.  
3. catalytic subunits phosphorylate Ser and Thr residues
3. catalytic subunits phosphorylate Ser and Thr residues
4. PKA can directly activate CREB, which binds CRE, altering the transcription
4. PKA can directly activate CREB, which binds CRE, altering the transcription
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Revision as of 22:24, 14 April 2013

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